|10/04/2007 - Influence of needling the foot-yangming points on intracellular Ca2+ concentration in smooth muscles of the gastric antrum in rabbits. |
Institute: Teaching and Research Section for Experimental Acupuncture, Department of Acupuncture and Massage, Hunan TCM College, Changsha 410007, China.
Author(s): Deng Y, Yi S, Lin Y, Yan J, Guo H, Xiang Z, Wu F, Liu W.
Journal: J Tradit Chin Med. 2007 Mar;27(1):65-9.
OBJECTIVE: To investigate the influence of acupuncture at the points of Foot-Yangming Meridian on intracellular concentration of Ca2, called the 2nd messenger of gastric smooth muscles.
METHODS: 45 rabbits were randomly divided into the following 5 groups: a normal saline group, a model group treated with atropine, an acupuncture group treated by needling the points of Foot-Yangming Meridian, an acupuncture group treated by needling the points of Foot-Shaoyang Meridian, an acupuncture group treated by needling the points of Foot-Taiyang Meridian, i.e. 9 rabbits in each group. After treatment, the smooth muscles of the gastric antrum were taken to make the suspension containing alive single muscular cells, and the intracellular calcium concentration ([Ca2+]i) was determined by a spectrofluorometer.
RESULTS: The concentration of [Ca2+]i in the group of Foot-Yangming Meridian was obviously higher than that of the atropine group (P<0.01), but with no significant differences found among all the other groups (P>0.05).
CONCLUSION: The influence of acupuncture at the points of Foot-Yangming Meridian on gastric movement is related to the release of intracellular Ca2+ in the gastric smooth muscles.